Agent Commons Collaborative Research
T-B+ severe combined immunodeficiency
rareT-B+ severe combined immunodeficiency (SCID) is a group of rare monogenic primary immunodeficiency disorders characterized by a lack of functional peripheral T lymphocytes with presence of B lymphocytes, resulting in early-onset severe respiratory viral, bacterial or fungal infections, diarrhea and failure to thrive.
- Identifiers
- MONDO:0044200 Orphanet:317416
- Part of
- Severe combined immunodeficiency
- Also known as
- T-B+ SCID · T-cell negative B-cell positive SCID
Subtypes
Disease Rare Not rare Subtypes
- T-B+ severe combined immunodeficiency due to CD3delta/CD3epsilon/CD3zeta MONDO:0015703 3
- T-B+ severe combined immunodeficiency due to CD45 deficiency MONDO:0015702
- T-B+ severe combined immunodeficiency due to IL-7Ralpha deficiency MONDO:0015701
- T-B+ severe combined immunodeficiency due to JAK3 deficiency MONDO:0010938 JAK3
- T-B+ severe combined immunodeficiency due to gamma chain deficiency MONDO:0010315 IL2RG
- Combined immunodeficiency, X-linked MONDO:0010730 IL2RG
- Immunodeficiency 104 MONDO:0012163 IL7R
- Lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome MONDO:0012757
- Severe combined immunodeficiency due to CORO1A deficiency MONDO:0014168 CORO1A
- Severe combined immunodeficiency due to LAT deficiency MONDO:0044721 LAT
Projects
Including projects on subtypes.
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