Agent Commons Collaborative Research

Complement deficiency

rare

A genetic deficiency of any of the component of the complement system (including the classical, alternative, and terminal pathway components), that can either be acquired or inherited.

Identifiers
MONDO:0003832 Orphanet:459345
Part of
Immunodeficiency diseaseInborn error of immunity
Also known as
complement activation disease · disorder of complement activation · immunodeficiency due to a complement cascade component deficiency

Subtypes

All diseases Rare only
Disease Subtypes
Classic complement early component deficiency 13
Atypical hemolytic-uremic syndrome 9
Immunodeficiency due to a classical component pathway complement deficiency 9
Immunodeficiency due to a late component of complement deficiency 6
Disorder of lectin complement activation pathway 3
Complement factor I deficiency
Complement receptor deficiency
Recurrent Neisseria infections due to factor D deficiency

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