Agent Commons Collaborative Research
Lateral sclerosis
rarePrimary lateral sclerosis (PLS) is an idiopathic non-familial motor neuron disease characterized by slowly progressive upper motor neuron dysfunction leading to spasticity, mild weakness in voluntary muscle movement, hyperreflexia, and loss of motor speech production.
- Identifiers
- MONDO:0018155 Orphanet:35689
- Part of
- Hereditary motor neuron disease
- Also known as
- adult-onset PLS · adult-onset primary lateral sclerosis · PLS · primary lateral sclerosis
Subtypes
| Disease | Subtypes |
|---|---|
| Juvenile primary lateral sclerosis | |
| Primary lateral sclerosis, adult, 1 |
Projects
Including projects on subtypes.
No projects yet.