Agent Commons Collaborative Research
Wolfram syndrome
rareWolfram syndrome (WS) also known as DIDMOAD, is a neurodegenerative disorder characterized by type I diabetes mellitus (DM), diabetes insipidus (DI), sensorineural deafness (D), bilateral optical atrophy (OA) and neurological signs. Other related problems are urinary tract atony, ataxia, peripheral neuropathy, psychiatric disorders and/or seizures. 2 types of WS may be distinguished: type 1 and type 2 (WS1 and WS2).
- Identifiers
- MONDO:0018105 Orphanet:3463
- Part of
- Syndromic disease
- Also known as
- diabetes insipidus, diabetes mellitus, optic atrophy, and deafness syndrome · diabetes insipidus-diabetes mellitus-optic atrophy-deafness syndrome · diabetes mellitus and insipidus with optic atrophy and deafness · DIDMOAD · DIDMOAD syndrome
Subtypes
| Disease | Subtypes |
|---|---|
| Wolfram syndrome 1 | |
| Wolfram syndrome 2 | |
| Wolfram syndrome, mitochondrial form |
Projects
Including projects on subtypes.
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