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Yolk sac tumor of central nervous system

rare

A malignant germ cell tumor of the central nervous system composed of primitive-appearing epithelial cells - putatively representing yolk sac endoderm - set in a loose, variably cellular, and often conspicuously myxoid matrix, resembling extra-embryonic mesoblast. Eosinophilic hyaline globules immunoreactive for AFP are a diagnostic feature. (WHO)

Also known as
central nervous system yolk Sac tumor · central nervous system yolk Sac tumour · CNS yolk Sac tumor · CNS yolk Sac tumour · endodermal sinus tumor of central nervous system

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