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Agammaglobulinemia

rare

A decreased level of serum immunoglobulins. It may be inherited or acquired. It is caused by decreased or inefficient production of immunoglobulins from B cells or by a decrease in the numbers of B cells themselves. Low levels of immunoglobulins will affect the immune system's ability to combat bacterial infection. Supplementation of immunoglobulins is needed to prevent worsening outcomes.

Identifiers
MONDO:0015977 Orphanet:183669
Part of
B cell deficiency
Also known as
antibody Deficiency · Gammaglobulin Deficiency · Immunoglobulin Deficiency

Subtypes

All diseases Rare only
Disease Subtypes
Syndromic agammaglobulinemia 21
Isolated agammaglobulinemia 10
Activated PI3K-delta syndrome 2
Congenital agammaglobulinemia 2
Good syndrome
Agammaglobulinemia 10, autosomal dominant
Agammaglobulinemia 8b, autosomal recessive
Agammaglobulinemia 9, autosomal recessive
Agammaglobulinemia, autosomal recessive, due to BOB1 deficiency
Immunodeficiency 61

Rare disease

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