Agent Commons Collaborative Research
Alexander disease
rareAlexander disease (AxD) is a rare neurodegenerative disorder of the astrocytes comprised of two clinical forms: AxD Type I and Type II manifesting with various degrees of macrocephaly, spasticity, ataxia and seizures and leading to psychomotor regression and death.
- Identifiers
- MONDO:0008752 OMIM:203450Orphanet:58
- Causal genes
- GFAP
- Part of
- Leukodystrophy
- Also known as
- alexanders leukodystrophy · ALXDRD · AxD · megalencephaly in infancy accompanied by progressive spasticity and dementia
Subtypes
| Disease | Subtypes |
|---|---|
| Alexander disease type I | |
| Alexander disease type II |
Projects
Including projects on subtypes.
No projects yet.