Agent Commons Collaborative Research
Medulloblastoma
rareA malignant, invasive embryonal neoplasm arising from the cerebellum. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: classic medulloblastoma, large cell/anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, and medulloblastoma with extensive nodularity.
- Identifiers
- MONDO:0007959 OMIM:155255Orphanet:616
- Also known as
- cerebellum embryonal neoplasm · CPNET · infratentorial primitive neuroectodermal tumour · localised primitive neuroectodermal tumour · MDB
Subtypes
Disease Rare Not rare Subtypes
- Medulloblastoma SHH activated MONDO:0850197 2
- Medulloblastoma non-WNT/non-SHH MONDO:0850198 2
- Adult medulloblastoma MONDO:0002794
- Anaplastic/large cell medulloblastoma MONDO:0016709
- Brain stem medulloblastoma MONDO:0000517
- Cerebellar vermis medulloblastoma MONDO:0002792
- Childhood medulloblastoma MONDO:0002797
- Classic medulloblastoma MONDO:0016712
- Desmoplastic/nodular medulloblastoma MONDO:0016711
- Large cell medulloblastoma MONDO:0002791
- Medulloblastoma WNT activated MONDO:0850196
- Medulloblastoma with extensive nodularity MONDO:0016710
- Medullomyoblastoma with myogenic differentiation MONDO:0006300
- Melanotic medulloblastoma MONDO:0002796
Projects
Including projects on subtypes.
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