Uveal melanoma
rareA melanoma derived from melanocytes of the uveal tract. It is the most common primary intraocular tumor in the United States and Western Europe. Similar to melanoma of the skin, it is rare in Africa and Asia. Diagnostic procedures include ophthalmoscopic exam, fluorescein angiography and ultrasound. Treatment includes: surgical excision of the eye, iridocyclectomy and tumor resection. Recent treatments also include radiotherapy or photo coagulation. Classification of uveal melanomas recognizes four cell types within these tumors: epithelioid, intermediate, mixed cell, and spindle cell types. The spindle cell type uveal melanomas are further sub-classified as spindle cell type A and spindle cell type B.
- Identifiers
- MONDO:0006486 OMIM:155720Orphanet:39044
- Part of
- Ocular melanomaUveal cancer
- Also known as
- intraocular melanoma · melanoma (disease) of uvea · melanoma of the uvea · melanoma of uvea · melanoma, uveal, malignant
Subtypes
- Iris melanoma MONDO:0004064 7
- Malignant choroid melanoma MONDO:0003878 5
- Intermediate cell type uveal melanoma MONDO:0004062 3
- Spindle cell intraocular melanoma MONDO:0003744 3
- Epithelioid cell uveal melanoma MONDO:0006200 2
- Mixed cell uveal melanoma MONDO:0003910 2
- Posterior uveal melanoma MONDO:0003927 2
- Necrotic uveal melanoma MONDO:0004365 1
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