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Testicular yolk sac tumor
rareA non-seminomatous malignant germ cell tumor arising from the testis. It affects infants, young children, and postpubertal males. It is the most frequently seen testicular neoplasm during childhood. The vast majority of patients present with an asymptomatic scrotal mass. The tumor mimics the yolk sac of the embryo and produces alpha-fetoprotein (AFP). It metastasizes to distant anatomic sites. Prognostic factors relate to the clinical stage and the degree of AFP elevation.
- Identifiers
- MONDO:0003402
- Also known as
- endodermal sinus tumour of testis · endodermal sinus tumour of the testis · endodermal-sinus tumor · endodermal-sinus tumour · Orchidoblastoma
Subtypes
Disease
- Enteric pattern testicular yolk sac tumor MONDO:0004543
- Polyvesicular vitelline pattern testicular yolk sac tumor MONDO:0004219
- Reticular pattern testicular yolk sac tumor MONDO:0004547
- Testicular yolk sac tumor, endodermal sinus pattern MONDO:0004178
- Testicular yolk sac tumor, glandular-alveolar pattern MONDO:0004402
- Testicular yolk sac tumor, hepatoid pattern MONDO:0004494
- Testicular yolk sac tumor, macrocystic pattern MONDO:0004106
- Testicular yolk sac tumor, myxomatous pattern MONDO:0004453
- Testicular yolk sac tumor, papillary pattern MONDO:0004493
- Testicular yolk sac tumor, solid pattern MONDO:0004198
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