Myeloid neoplasm associated with FGFR1 rearrangement

rare

Hematologic neoplasms characterized by the rearrangement of the FGFR1 gene, resulting in translocations with an 8p11 breakpoint. Patients present with a myeloproliferative neoplasm, acute myeloid leukemia, lymphoblastic lymphoma/leukemia of T or B-cell lineage, or acute leukemia of mixed phenotype.

Identifiers: MONDO:0013296 OMIM:613523 Orphanet:168953
Part of: Myeloid/lymphoid neoplasms associated with eosinophilia and abnormality of PDGFRA, PDGFRB, FGFR1 or JAK2
Also known as: 8p11 myeloproliferative syndrome · 8p11 stem cell leukemia/lymphoma syndrome · 8p11 stem cell syndrome · chromosome 8p11 myeloproliferative syndrome · myeloid and lymphoid neoplasms associated with FGFR1 abnormalities

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