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Growth delay due to insulin-like growth factor I resistance
rareGrowth delay due to IGF-I resistance is characterized by variable intrauterine and postnatal growth retardation and elevated serum IGF-I levels. Addition features include variable degrees of intellectual deficit, microcephaly and dysmorphism (broad nasal bridge and tip, smooth philtrum, thin upper and everted lower lips, short fingers, clinodactyly, wide-set nipples and pectus excavatum).
- Identifiers
- MONDO:0010038 OMIM:270450Orphanet:73273
- Causal genes
- IGF1R
- Also known as
- IGF-1 resistance · IGF1RES · insulin-like growth factor 1 resistance to · resistance to IGF-1 · Somatomedin end-organ insensitivity to
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