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Familial partial lipodystrophy, Dunnigan type
rareFamilial Partial lipodystrophy, Dunnigan type (FPLD2) is a rare form of genetic lipodystrophy characterized by a loss of subcutaneous adipose tissue from the trunk, buttocks and limbs; fat accumulation in the neck, face, axillary and pelvic regions; muscular hypertrophy; and usually associated with metabolic complications such as insulin resistance, diabetes mellitus, dyslipidemia and liver steatosis.
- Identifiers
- MONDO:0007906 OMIM:151660Orphanet:2348
- Causal genes
- LMNA
- Also known as
- Dunnigan syndrome · familial partial lipodystrophy type 2 · FPL2 · FPLD2 · lipodystrophy, familial partial, type 2
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